Publications

2021

Han, Samuel, Jennifer M Kolb, Patrick Hosokawa, Chloe Friedman, Charlie Fox, Frank I Scott, Christopher H Lieu, et al. (2021) 2021. “The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry.”. The American Journal of Gastroenterology 116 (4): 811-15. https://doi.org/10.14309/ajg.0000000000001046.
Publisher's Version
Publisher's Version

INTRODUCTION: Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.

METHODS: We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.

RESULTS: In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).

DISCUSSION: This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

Vajravelu, Ravy K, Lawrence Copelovitch, and Michelle R Denburg. (2021) 2021. “Reply.”. Clinical Gastroenterology and Hepatology : The Official Clinical Practice Journal of the American Gastroenterological Association 19 (9): 1994. https://doi.org/10.1016/j.cgh.2020.11.031.
Publisher's Version
Publisher's Version
Han, Samuel, Jennifer M Kolb, Patrick Hosokawa, Chloe Friedman, Charlie Fox, Frank I Scott, Christopher H Lieu, et al. (2021) 2021. “The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry.”. The American Journal of Gastroenterology 116 (4): 811-15. https://doi.org/10.14309/ajg.0000000000001046.
Publisher's Version
Publisher's Version

INTRODUCTION: Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.

METHODS: We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.

RESULTS: In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).

DISCUSSION: This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

Vajravelu, Ravy K, Lawrence Copelovitch, and Michelle R Denburg. (2021) 2021. “Reply.”. Clinical Gastroenterology and Hepatology : The Official Clinical Practice Journal of the American Gastroenterological Association 19 (9): 1994. https://doi.org/10.1016/j.cgh.2020.11.031.
Publisher's Version
Publisher's Version
Han, Samuel, Jennifer M Kolb, Patrick Hosokawa, Chloe Friedman, Charlie Fox, Frank I Scott, Christopher H Lieu, et al. (2021) 2021. “The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry.”. The American Journal of Gastroenterology 116 (4): 811-15. https://doi.org/10.14309/ajg.0000000000001046.
Publisher's Version
Publisher's Version

INTRODUCTION: Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.

METHODS: We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.

RESULTS: In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).

DISCUSSION: This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

Vajravelu, Ravy K, Lawrence Copelovitch, and Michelle R Denburg. (2021) 2021. “Reply.”. Clinical Gastroenterology and Hepatology : The Official Clinical Practice Journal of the American Gastroenterological Association 19 (9): 1994. https://doi.org/10.1016/j.cgh.2020.11.031.
Publisher's Version
Publisher's Version
Han, Samuel, Jennifer M Kolb, Patrick Hosokawa, Chloe Friedman, Charlie Fox, Frank I Scott, Christopher H Lieu, et al. (2021) 2021. “The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry.”. The American Journal of Gastroenterology 116 (4): 811-15. https://doi.org/10.14309/ajg.0000000000001046.
Publisher's Version
Publisher's Version

INTRODUCTION: Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.

METHODS: We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.

RESULTS: In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).

DISCUSSION: This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

Vajravelu, Ravy K, Lawrence Copelovitch, and Michelle R Denburg. (2021) 2021. “Reply.”. Clinical Gastroenterology and Hepatology : The Official Clinical Practice Journal of the American Gastroenterological Association 19 (9): 1994. https://doi.org/10.1016/j.cgh.2020.11.031.
Publisher's Version
Publisher's Version
Han, Samuel, Jennifer M Kolb, Patrick Hosokawa, Chloe Friedman, Charlie Fox, Frank I Scott, Christopher H Lieu, et al. (2021) 2021. “The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry.”. The American Journal of Gastroenterology 116 (4): 811-15. https://doi.org/10.14309/ajg.0000000000001046.
Publisher's Version
Publisher's Version

INTRODUCTION: Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.

METHODS: We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.

RESULTS: In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).

DISCUSSION: This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

Vajravelu, Ravy K, Lawrence Copelovitch, and Michelle R Denburg. (2021) 2021. “Reply.”. Clinical Gastroenterology and Hepatology : The Official Clinical Practice Journal of the American Gastroenterological Association 19 (9): 1994. https://doi.org/10.1016/j.cgh.2020.11.031.
Publisher's Version
Publisher's Version