The University of Florida College of Pharmacy has received a $3.6 million grant from the National Institute on Drug Abuse (NIDA) to fund the PROTECT project, which will develop an artificial intelligence–powered clinical tool to predict and prevent relapse among individuals receiving buprenorphine treatment for opioid use disorder. The tool aims to support clinicians by identifying patients at elevated risk of relapse and enabling earlier, targeted interventions. The multi-institutional research team includes CP3 faculty members Dr. Jenny Lo-Ciganic and Dr. Walid Gellad as co-investigators from the University of Pittsburgh, who will contribute expertise in machine learning, real-world data, and clinical implementation. The PROTECT project represents a significant step toward integrating AI into addiction care to improve outcomes and advance precision treatment approaches for opioid use disorder.