Unigwe, Ikenna, Amie Goodin, Wei-Hsuan Lo-Ciganic, Robert L Cook, and Haesuk Park. 2024. “Trajectories of Pre-Exposure Prophylaxis Adherence Among Commercially Insured Individuals.”. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America 78 (5): 1272-75.
Abstract
We used group-based trajectory models to identify 4 distinct trajectory patterns of adherence to preexposure prophylaxis (PrEP) among 20 696 users. Only 44.5% were consistently PrEP adherent, with younger age, being female, or having substance use disorder or depression associated with early discontinuation. Public health efforts are needed to improve PrEP adherence.